Cytotoxic Studies on Two Meliaceae plants: Chukrasia Tabularis and Aglaia Roxburghiana
نویسندگان
چکیده
منابع مشابه
Kv1.2 potassium channel inhibitors from Chukrasia tabularis.
Eighteen new limonoids, chubularisins A-R (1-18), along with eleven known analogues, were isolated from the stem bark of Chukrasia tabularis. The structures of 1-18 were elucidated on the basis of spectroscopic data and chemical evidence. Compound 1 represented the first example of 8,9,12-orthoester of phragmalin limonoids. Interestingly, compounds 4, 8, and 22 exhibited potent and selective in...
متن کاملTwo new phragmalin-type limonoids from Chukrasia tabularis var. velutina.
Two new phragmalin-type limonoids with different structural skeletons, chuktabrin K (1) and tabulalin J (2), were isolated from the stem barks of Chukrasia tabularis var. velutina in the course of our ongoing research work in this area. Compound 1 was a 16-norphragmalin with an enolic alkyl appendage at C-15, and the carbonate moiety in 1 was also rare in natural organic molecules. The basic sk...
متن کاملPharmacognostical Studiies on Aglaia Roxburghiana Miq. Var. Beddomei
Morphological, anatomical, quantitative microscopy powder microscopy, physical constant preliminary phytochemical analysis and fluorescence analysis of the leaves of Aglaia roxburghiana Var. Beddome were carried out.
متن کاملPhragmalin-type limonoid orthoesters from Chukrasia tabularis var. velutina.
Nine new phragmalin-type limonoid orthoesters, tabulalides F-N (1-9), together with three known compounds, tabulalides C and D, and tabularisin N (10-12), were isolated from the stem bark of Chukrasia tabularis var. velutina. Extensive spectroscopic technologies were applied to elucidate the structures of these new compounds, including the application of circular dichroism (CD) exciton chiralit...
متن کاملTwo new phragmalin-type limonoids from Chukrasia tabularis and their α-glucosidase inhibitory activity.
Phytochemical investigation on the stems of C. tabularis (Meliaceae) led to the isolation of two new phragmalin-type limonoids, named tabularisins S and T (1-2), along with five known ones (3-7). The structures of the new limonoids were established by spectroscopic methods including UV, IR, HRESIMS, and 1D and 2D NMR. All the compounds were evaluated for α-glucosidase inhibitory activity in vit...
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ژورنال
عنوان ژورنال: Journal of Scientific Research
سال: 2009
ISSN: 2070-0245,2070-0237
DOI: 10.3329/jsr.v1i2.1645